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Oxford Sparks Big Questions

Aug 3, 2016

Once we've received our genetic make-up from our parents our genomes are stable, right? What causes mutations in our DNA as we live and grow, and how do our cells repair damage? We all know we should be careful when in the sun, but Prof Catherine Green's interests lie in understanding how Human cells manage to copy the enormous amounts of DNA they have without making mistakes and how they cope with threats; like sunlight. Cath describes what happens when DNA gets damaged and how her work seeks to understand the cellular machinery involved in copying and repairing DNA. She also discusses other threats and risks, how other animals protect themselves from sunlight and how understanding these processes better will help us understand disorders, everyone's risks and develop more targeted treatments.